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Umbilical and uterine Doppler velocimetry and prostaglandin levels in preeclampsia
Author(s) -
Feinkind L,
Nanda D,
Minkoff H
Publication year - 1992
Publication title -
journal of ultrasound in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 91
eISSN - 1550-9613
pISSN - 0278-4297
DOI - 10.7863/jum.1992.11.2.77
Subject(s) - medicine , prostacyclin , umbilical artery , thromboxane , preeclampsia , laser doppler velocimetry , thromboxane b2 , umbilical vein , radioimmunoassay , velocimetry , placenta , endocrinology , fetus , pregnancy , blood flow , platelet , biochemistry , chemistry , physics , biology , optics , in vitro , genetics
Eleven preterm patients with severe preeclampsia underwent Doppler velocimetry prior to cesarean section. Maternal venous blood and umbilical arterial and venous samples were collected for prostacyclin and thromboxane determination by radioimmunoassay. Umbilical artery pulsatility index correlated positively with umbilical artery thromboxane B2 levels (r = 0.76; P less than 0.05) and maternal thromboxane levels (r = 0.78; P less than 0.05). We conclude that the vasoactive action of thromboxane A2 may alter placental resistance.