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Neurosonographic changes in newborns treated with extracorporeal membrane oxygenation.
Author(s) -
Luisiri A,
Graviss E R,
Weber T,
Silberstein M J,
Tantana S,
Connors R,
Brodeur A E
Publication year - 1988
Publication title -
journal of ultrasound in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 91
eISSN - 1550-9613
pISSN - 0278-4297
DOI - 10.7863/jum.1988.7.8.429
Subject(s) - medicine , extracorporeal membrane oxygenation , intraventricular hemorrhage , periventricular leukomalacia , infarction , hypoxia (environmental) , ischemia , echogenicity , oxygenation , cerebral infarction , incidence (geometry) , anesthesia , cardiology , surgery , myocardial infarction , ultrasonography , gestational age , pregnancy , chemistry , physics , organic chemistry , biology , oxygen , optics , genetics
Ten out of 40 near‐term neonates on extracorporeal membrane oxygenation (ECMO) therapy developed abnormal neurosonograms. We identified two abnormal patterns. Hyperechoic areas of intracranial hemorrhage were observed in two patients (a significantly lower incidence than previously reported). Diffuse or focal echogenic areas of hypoxia‐ischemia resulting from periventricular leukomalacia, cerebral edema or large vessel infarction had not previously been noted in nine of these patients. Three of the ten patients survived with neurological sequelae. Recognition of hemorrhage or a hypoxic‐ischemic pattern should serve as a warning to initiate or accelerate the weaning of infants from ECMO.