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The effects of diagnostic ultrasonography on the frequencies of sister chromatid exchanges in Chinese hamster cells and human lymphocytes.
Author(s) -
Wegner R D,
Meyenburg M
Publication year - 1982
Publication title -
journal of ultrasound in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 91
eISSN - 1550-9613
pISSN - 0278-4297
DOI - 10.7863/jum.1982.1.9.355
Subject(s) - sister chromatids , chinese hamster ovary cell , medicine , metaphase , mitosis , sister chromatid exchange , cell cycle , chromatid , hamster , microbiology and biotechnology , andrology , genetics , chromosome , biology , in vitro , receptor , cancer , gene
Human lymphocytes as well as Chinese hamster ovary cells were sonicated with either a fetal pulse detector (Siemens, Eucotone) or a compound scanner (Kretz, Combison 4100) at diagnostic energy levels. In one experimental series the cells were treated in the G1‐phase of the cell cycle, in the other during late S‐phase. The frequency of sister chromatid exchanges was determined in the metaphase chromosomes of the following mitosis. No significant increase in the frequency of SCEs per cell was observed as compared with the controls.