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Sonography as a procedure complementary to alpha‐fetoprotein testing for neural tube defects.
Author(s) -
Slotnick N,
Filly R A,
Callen P W,
Golbus M S
Publication year - 1982
Publication title -
journal of ultrasound in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 91
eISSN - 1550-9613
pISSN - 0278-4297
DOI - 10.7863/jum.1982.1.8.319
Subject(s) - medicine , neural tube , amniocentesis , neural tube defect , ultrasound , amniotic fluid , fetus , prenatal diagnosis , alpha fetoprotein , alpha (finance) , pregnancy , obstetrics , radiology , surgery , embryo , construct validity , genetics , patient satisfaction , biology , microbiology and biotechnology , hepatocellular carcinoma
Forty‐four fetuses were studied sonographically because of an elevated amniotic fluid alpha‐fetoprotein level noted during routine amniocentesis, questionable findings during an ultrasound examination at another institution, or a history of a neural tube defect in prior pregnancy. Eleven neural tube defects, 16 non‐neural tube defect anomalies, and 17 normal fetuses were all correctly identified by sonography. Ultrasound answers the need for a second diagnostic tool to complement the alpha‐fetoprotein measurement.