Open AccessAxillary Lymph Nodal Metastasis from Carcinoma of Unknown Primary (CUPAx)- An Orphan Disease
Author(s) -
Renuka Bangalore Nagaraj,
Khursid Alam Ansari
Publication year - 2021
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2021/51002.15177
Subject(s) - medicine , axilla , axillary lymph nodes , metastasis , adenocarcinoma , lymph node , immunohistochemistry , mammography , lymph , breast carcinoma , carcinoma , pathology , radiology , oncology , breast cancer , cancer
Metastasis to axillary lymph node occurs in adenocarcinoma or poorly differentiated carcinoma, and is a rare clinical entity that needs to be understood for management and its clinical outcome. The present case is of 72-year-old female patient who had a metastatic nodule in the axilla. No breast mass was palpable. Histology identified as metastatic adenocarcinoma, however mammography and Ultrasound Sonography test (USg) failed to detect the primary tumour. Immunohistochemistry showed that the excised lymph node was positive for Estrogen Receptor (ER) and negative for Progesterone Receptor (PR), suggesting the breast as the site for the primary tumour. Since the patient refused surgery, she was under follow-up for eight months. Now, she presented with recurrence of similar axillary swelling for two months.