Open AccessNodular Subcutaneous Phaeohyphomycosis due to Medicopsis romeroi in an Immunocompetent Patient
Author(s) -
Smita Deshkar,
Niranjan Patil,
Ashish Lad,
Shraddha Amberkar,
Swati Sharan
Publication year - 2021
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2021/50213.15244
Subject(s) - phaeohyphomycosis , itraconazole , nodule (geology) , medicine , dermatology , antifungal , subcutaneous tissue , pathology , biology , paleontology
Fungal infections like subcutaneous phaeohyphomycosis are uncommon but are increasing lately, especially in tropical regions like India. Identification of correct aetiologic agent is essential as different species can have different organ tropism. Here, a rare case of nodular subcutaneous phaeohyphomycosis in an immunocompetent 62-year-old male patient who developed nodule over right dorsum of foot is reported. After various diagnostic tests a rare dematiaceous fungus Medicopsis romeroi was identified as a causative agent in the nodular material by Internal Transcribed Spacer (ITS) sequencing. Surgical excision and antifungal therapy of itraconazole proved beneficial with no recurrence during a six months of follow-up. Medicopsis romeroi has been debated for its role in human infections however, it should be considered as one of the aetiologic agents of subcutaneous phaeohyphomycosis.