Open AccessRecurrent Thymoma Mimicking T-Lymphoblastic Lymphoma: An Unusual Case Presentation
Author(s) -
Kalasamudram Sravani,
Pranabandhu Das,
Bala Subramanian,
TC Kalawat,
Nandyala Rukmangadha
Publication year - 2021
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2021/48687.15451
Subject(s) - thymoma , medicine , lymphoblastic lymphoma , mediastinum , lymphoma , radiation therapy , thymus neoplasm , presentation (obstetrics) , radiology , pathology , thymic carcinoma , t cell , immunology , immune system
Thymoma and T-Lymphoblastic Lymphomas (T-LBL) are primary mediastinal neoplasms that can have similar clinical presentations and overlapping histological features. Because of immature lymphocytes associated with thymoma, it may resemble T-LBL. In this present case report, a 20-year-old male patient with recurrent unresectable thymoma has received definitive chemoradiation therapy. Significant reduction of gross tumour volume was observed while patient underwent weekly image verification before radiotherapy at the end of fourth week, causing the suspicious about the possibility of a highly radiosensitive tumour in mediastinum like lymphoma or extragonadal germ cell tumour. External review of immumohistochemistry features were suggestive of T-LBL.