Open AccessRole of Plasma Exchange in Steroid Resistant Neuromyelitis Optica with Loss of Vision
Author(s) -
Ashish Maheshwari,
Dnyaneshwar Shridharrao Patale,
Trupti Lokhande,
Smita Chouhan,
Sana Mariyam
Publication year - 2020
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2020/45701.14115
Subject(s) - neuromyelitis optica , medicine , apheresis , optic nerve , optic neuritis , therapeutic plasma exchange , spinal cord , treatment modality , multiple sclerosis , dermatology , surgery , ophthalmology , immunology , psychiatry , platelet
Neuromyelitis Optica (NMO) is a demyelinating inflammatory disorder of the spinal cord and optic nerve. As per American Society For Apheresis (ASFA) guidelines, Therapeutic Plasma Exchange (TPE) is considered as a second-line treatment in patients with weak or no response to steroid therapy. A patient of NMO presented to the tertiary care institute with a sudden loss of vision in the right eye. The patient was resistant to steroid treatment and improved significantly with TPE. Hence, TPE may be an effective treatment modality in steroid-resistant NMO with vision loss.