Open AccessLipid Profile as a Nutritional Status Marker in Tuberculosis
Author(s) -
Vaishnavi Sandip Salunkhe,
Vinayak W. Patil,
Preeti Rai
Publication year - 2020
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2020/45522.14266
Subject(s) - lipid profile , medicine , very low density lipoprotein , cholesterol , malnutrition , immune status , tuberculosis , lipoprotein , low density lipoprotein , gastroenterology , immune system , high density lipoprotein , physiology , immunology , pathology
Introduction: Tuberculosis (TB) is a global health problem. India has the highest cases in the world and accounts for nearly one fifth of global cases. TB is a chronic disease and in long term leads to malnutrition. Lipids are important constituents in the body that determine the nutritional status and immune function. Aim: To study lipid profile as a nutritional status marker in pulmonary TB. Materials and Methods: Fifty patients of pulmonary TB and fifty healthy subjects in age group of 18-60 years were included for study. The lipid profile was analysed to assess the nutritional status of the patients. Unpaired t-test was used to study the significance of study parameters in cases and controls group. The p-value of <0.05 was considered to be statistically significant. Results: Out of 100 subjects 63% were males 37% were females. Significant decreased levels of total cholesterol, Triglycerides, High Density Lipoprotein-Cholesterol (HDL), Very Low Density Lipoprotein-Cholesterol (VLDL), Low Density Lipoprotein-Cholesterol (LDL) were seen in cases as compared to controls. Conclusion: In this study, it was observed that lipid profile could play a significant role as a biochemical marker of nutritional status in pulmonary TB patients. Thus, knowledge of these levels can help in providing a proper balanced diet to these patients which can ultimately help in better quality treatment.