Open AccessA Case of Macrophagic Activation Syndrome in a Child with Epilepsy Treated with an Excessive Dose of Sodium Valproate
Author(s) -
Kambourou Judicael,
. Moyen-Engoba,
Oko Aymar Pierre Gildas,
Lethso Thibaut Ocko Gokaba,
Olivia Firmine Atipo Galiba
Publication year - 2020
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2020/44447.13950
Subject(s) - pancytopenia , pediatrics , medicine , epilepsy , intensive care unit , psychiatry , bone marrow
Macrophagic Activation Syndrome (MAS) is a rare disorder and is thought to result from non-malignant activation and proliferation of macrophages and T-cells. It can be of primary or secondary origin and its prognosis is often poor. Authors report a case of a three-year-old boy admitted in the intensive care unit for MAS secondary to an overdose of sodium valproate to remind practitioners to think about it in the presence of a febrile pancytopenia.