Open AccessHistomorphologic Spectrum in Hyaline Vascular Variant of Castleman Disease
Author(s) -
Chaithra Gowthuvalli Venkataramana,
Hema Kini,
Debarshi Saha,
Sharada Rai,
Deepa Adiga,
Ranjitha Rao,
Cheryl Sarah Philipose
Publication year - 2017
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2017/29415.10326
Subject(s) - hyaline , pathology , germinal center , pathological , medicine , b cell , immunology , antibody
Castleman Disease (CD) is a rare lymphopro-liferative disorder with heterogenous clinical and pathological features. It is a rare disease with mention in the rare disease data of the orphanet. It can present as unicentric or multicentric disease. Hyaline vascular variant and plasma cell variant are the two pathological subtypes. Hyaline vascular variant accounts for nearly 80% to 90% of unicentric cases. Hyaline vascular subtype variant has follicular and stroma rich subtype.