Open AccessEffect of Agonist and Antagonist on the In Vitro Contractility of Inflamed Vermiform Appendix
Author(s) -
Phani Bhushan Singh,
Pushpakant Tiwary,
Sanjeev K. Singh,
R. K. Pandey,
A Roy,
Amrita Kar,
Somprakas Basu,
Anil Kumar Tiwari
Publication year - 2017
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2017/28804.10124
Subject(s) - vermiform , histamine , contractility , appendix , agonist , atropine , contraction (grammar) , muscle contraction , acetylcholine , medicine , serotonin , endocrinology , antagonist , methysergide , chemistry , biology , receptor , paleontology
Appendicitis poses a great health problem worldwide. Previous studies demonstrated structural damage to neuronal network and interstitial cell of Cajal in appendicitis. Above observations suggest for the alterations in appendicular motility/contractility in appendicitis. But the mechanisms involved in mediating the contractility in inflamed vermiform appendix is not known till date.