Approach to a Pregnant Woman with Anti D + Anti C Reactivity Pattern: A Diagnostic Conundrum | Zendy

Preeti Rai | Zendy; Geetika Sharma | Zendy; Deeksha Singh | Zendy; Jyoti Garg | Zendy

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Approach to a Pregnant Woman with Anti D + Anti C Reactivity Pattern: A Diagnostic Conundrum

Author(s) -

Preeti Rai,

Geetika Sharma,

Deeksha Singh,

Jyoti Garg

Publication year - 2017

Publication title -

journal of clinical and diagnostic research

Language(s) - English

Resource type - Journals

eISSN - 2249-782X

pISSN - 0973-709X

DOI - 10.7860/jcdr/2017/27902.10550

Subject(s) - reactivity (psychology) , hemolytic disease of the newborn (abo) , antigen , medicine , pregnancy , immunology , disease , fetus , chemistry , biology , genetics , pathology , alternative medicine

The Rhesus G antigen is present on all RBCs that are C+ and also on most D+ RBCs. Due to this co-distribution of G with either C or D antigen, it mimics a reactivity pattern of anti C + anti D on Indirect Antiglobulin Test (IAT), though the role of Anti G in causing Hemolytic Disease of Newborn (HDN) is controversial. The differentiation of anti D, anti C, and anti G is essential particularly in pregnant females. We hereby report a rare case of anti G with anti D and anti C in a pregnant woman with emphasis on approach to identify anti D+C+G and its implications.

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