Open AccessApproach to a Pregnant Woman with Anti D + Anti C Reactivity Pattern: A Diagnostic Conundrum
Author(s) -
Preeti Rai,
Garima Sharma,
D Singh,
Jyoti Garg
Publication year - 2017
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2017/27902.10550
Subject(s) - reactivity (psychology) , hemolytic disease of the newborn (abo) , antigen , medicine , pregnancy , immunology , disease , fetus , chemistry , biology , genetics , pathology , alternative medicine
The Rhesus G antigen is present on all RBCs that are C+ and also on most D+ RBCs. Due to this co-distribution of G with either C or D antigen, it mimics a reactivity pattern of anti C + anti D on Indirect Antiglobulin Test (IAT), though the role of Anti G in causing Hemolytic Disease of Newborn (HDN) is controversial. The differentiation of anti D, anti C, and anti G is essential particularly in pregnant females. We hereby report a rare case of anti G with anti D and anti C in a pregnant woman with emphasis on approach to identify anti D+C+G and its implications.