
Fabrication and Appraisal of Poly (Lactic-Co-Glycolic Acid) – Moxifloxacin Nanoparticles using Vitamin E-TPGS: A Potential Intracanal Drug Delivery Agent
Author(s) -
Hardik Makkar
Publication year - 2017
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2017/27633.9957
Subject(s) - moxifloxacin , enterococcus faecalis , plga , biodegradable polymer , chitosan , nuclear chemistry , drug delivery , calcium hydroxide , chemistry , glycolic acid , materials science , nanoparticle , polymer , nanotechnology , lactic acid , organic chemistry , biochemistry , escherichia coli , gene , antibiotics , genetics , biology , bacteria
Nanotechnology is gaining momentum in the search for ideal biomaterials by dental researchers. The expansible nature of Endodontology deems exploration, learning and scrutinizing newer avenues which have the potential to be applied and investigated. The popularity of polymers as drug delivery vehicles has opened avenues for their application in the root canal system. This study utilized application of biodegradable polymers as potential drug delivery vehicles against Enterococcus faecalis , one of the main reasons for post treatment disease.