Open AccessCombined Thrombophilia in a Young Male Presenting as Life Threatening Pulmonary Embolism
Author(s) -
Akshyaya Pradhan,
Ayush Shukla,
Mili Jain,
A. Mehrotra,
Rishi Sethi
Publication year - 2017
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2017/27336.10582
Subject(s) - thrombophilia , medicine , pulmonary embolism , thrombosis , protein s deficiency , factor v leiden , pediatrics , venous thrombosis
Combined hereditary thrombophilia is an uncommon entity associated with higher risk of early onset thrombosis. We report a case of 39-year-old male with combined deficiency of natural anticoagulants (protein C, S and anti thrombin) along with hyper homocystenemia and factor V Leiden mutation, presenting with life threatening bilateral pulmonary embolism. The clinical implications of combined thrombophilia are also discussed.