Open AccessEvaluation of Acute Oral Toxicity of Ethanol Leaves Extract of Catharanthus roseus in Wistar Albino Rats
Author(s) -
Venkateswar Rao Vutukuri,
Moyuri Das,
M. Lava Kumar Reddy,
Siva Prabodh,
Sunethri Padma
Publication year - 2017
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2017/24937.9325
Subject(s) - catharanthus roseus , creatinine , toxicity , lactate dehydrogenase , acute toxicity , pharmacology , urea , medicine , traditional medicine , biology , biochemistry , enzyme
Herbal drugs have gained importance globally in the treatment of various diseases. Catharanthus roseus is traditionally used as an anti diabetic and anti cancer drug. To the best of our knowledge limited data are available on acute and sub acute toxicity of C. roseus extract despite its wide spread use in traditional medicine. The present study was under taken to evaluate the acute oral toxicity of the ethanol leaves extract of C. roseus .