Open AccessA Comparative Study on Clinical and Biochemical Parameters in Amlodipine and Cilnidipine Treated Hypertensive Patients
Author(s) -
Kiran Kumar Shetty,
Ranjan Shetty,
Lakshminarayana Bairy,
Pragna Rao,
Amruth Kiran,
Manjunath Shetty,
. Deepak,
Krishnananda Nayak
Publication year - 2017
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2017/23825.9763
Subject(s) - amlodipine , medicine , dihydropyridine , blood pressure , creatinine , nimodipine , essential hypertension , endocrinology , gastroenterology , calcium
Hypertension is a major health issue worldwide. Calcium Channel Blockers (CCBs) are the most commonly used antihypertensive agents. CCBs act on voltage-dependent calcium channels and they were categorized into two subclasses, Dihydropyridine (DHP) and non-Dihydropyridine (non-DHP) derivative. Amlodipine is a third generation L-type of DHP and Cilnidipine is a novel L/N-type of DHP CCB, both drugs have excellent pharmacological profiles with the unique actions.