Open AccessGamma Glutamyl Transpeptidase, Smokeless Tobacco, Chronic Periodontitis: Exploring the Link
Author(s) -
Koregol Ac,
Kalburgi Nb,
Wagh Auk,
Shivaraj Warad
Publication year - 2017
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2017/23598.9476
Subject(s) - smokeless tobacco , chronic periodontitis , medicine , periodontitis , biomarker , oxidative stress , gastroenterology , pathogenesis , dentistry , pathology , tobacco use , environmental health , biology , biochemistry , population
Oxidative Stress (OS) is implicated in the pathogenesis of many systemic and oral diseases such as periodontal disease. Smokeless tobacco extract produces apoptosis and causes an imbalance between reactive oxygen species and antioxidants, such as Gamma Glutamyl Transpeptidase (GGT). Epidemiological research implied serum GGT within its normal range to be an early sensitive enzyme related to OS.