Open AccessErythrocyte Alloimmunization and Autoimmunization among Blood Donors and Recipients visiting a Tertiary Care Hospital
Author(s) -
Daljit Kaur,
Lovenish Bains,
Manoj Kandwal,
Indu Parmar
Publication year - 2017
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2017/22904.9401
Subject(s) - medicine , abo blood group system , antibody , autoantibody , immunology , blood grouping , population , ethylene diamine , gastroenterology , chemistry , environmental health , nuclear chemistry
The ultimate aim of pretransfusion testing is the acceptable survival of donor red cells in recipient's body and antibody detection plays a critical role in achieving the same. The cornerstone of antibody detection method is detecting an unexpected antibody as against the expected antibodies of ABO blood group system. Autoantibodies can also interfere with the detection of clinically significant alloantibodies.