Open AccessParaneoplastic Glomerulopathy in a Case of Collecting Duct Renal Cell Carcinoma
Author(s) -
Srikanth Prasad Devarsetty,
Dharshan Rangaswamy,
Shailaja S Bhat,
Shankar Prasad Nagaraju,
Ravindra Prabhu Attur
Publication year - 2017
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2017/21784.9233
Subject(s) - medicine , nephrotic syndrome , renal cell carcinoma , pathology , membranous nephropathy , adenocarcinoma , glomerulopathy , gastrointestinal tract , renal biopsy , carcinoma , biopsy , kidney , glomerulonephritis , gastroenterology , cancer
Paraneoplastic glomerulopathy has been described in established cases of the solid tumors of lung, gastrointestinal system, breast, etc., and rarely in patients with Renal Cell Carcinoma (RCC). Studies on secondary glomerular diseases have described a higher incidence of IgA nephropathy in patients with RCC compared to membranous glomerulopathy, which are commonly reported in malignancies of the lung and gastrointestinal tract. Collecting Duct Carcinoma (CDC), a rare high grade adenocarcinoma accounts for <1% of all renal malignancies. It arises from the cells of the collecting ducts of Bellini. We report a case of an elderly male who was diagnosed to have a disseminated CDC during his evaluation for nephrotic syndrome. Renal biopsy was suggestive of a secondary membranous glomerulonephropathy.