Open AccessBCL6 mRNA Expression Level in Invasive Duct Carcinoma not otherwise Specified
Author(s) -
Eman Badr,
Eman Masoud,
Asmaa Gaber Abdou,
Marwa Serag El-Dien
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/22796.8985
Subject(s) - bcl6 , cancer research , breast cancer , carcinogenesis , medicine , fibroadenoma , pathology , biology , oncology , cancer , immunology , b cell , germinal center , antibody
B-Cell Lymphoma 6 (BCL6) has an oncogenic role in tumourigenesis of various malignancies. It represses genes involved in terminal differentiation and plays complementary role with Signal Transducer and Activator of Transcription 3 (STAT3) in triple-negative breast cancer cellular function.