Open AccessO’Brien’s Granuloma- A Case Report
Author(s) -
Pratik Thacker,
Kashinath Nayak,
Flora D. Lobo,
Pavithra Govindasamy
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - Uncategorized
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/22772.8675
Subject(s) - granuloma annulare , sarcoidosis , histiocyte , pathology , granuloma , medicine , histopathology , pathogenesis , dermatology , population , environmental health
Actinic granuloma is a self-limiting chronic disorder with elastolytic granulomas, mainly of the sun exposed skin and unknown pathogenesis. We report a case of a middle aged woman with multiple annular erythematous lesions. Histopathology revealed degenerated elastic fibres with histiocyte aggregates surrounded by multiple giant cells suggestive of elastolytic granulomas. She also had associated dyslipidemia and hypothyroidism. Actinic granuloma is relatively rare in the Indian population and needs to be differentiated from conditions like sarcoidosis and granuloma annulare.