Open AccessPolymerase Chain Reaction: An Important Tool for Early Diagnosis of Leptospirosis Cases
Author(s) -
Summaiya Mullan,
Tanvi Panwala
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/22462.9010
Subject(s) - leptospirosis , leptospira , direct agglutination test , polymerase chain reaction , serology , medicine , gold standard (test) , serotype , antibody , virology , immunology , biology , biochemistry , gene
Various diagnostic methods like Microscopic Agglutination Test (MAT), IgM ELISA, Isolation of Leptospira from the clinical specimen, Rapid leptocheck tests etc., are available for diagnosis of leptospirosis. Polymerase Chain Reaction (PCR) is used for diagnosis of various diseases of infectious origin including leptospirosis but there is paucity of data about comparison of PCR with other available method of diagnosis of leptospirosis.