Open AccessAssessment of Serum VASPIN Levels among Type 2 Diabetes Mellitus Patients with or without Acute Coronary Syndrome
Author(s) -
Aswathy Jaya Sathyaseelan,
Prashant Shankarrao Adole,
Mukta Wyawahare,
Rama Prakasha Saya
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/22417.8952
Subject(s) - medicine , acute coronary syndrome , type 2 diabetes mellitus , informed consent , ethics committee , diabetes mellitus , type 2 diabetes , endocrinology , alternative medicine , pathology , political science , myocardial infarction , public administration
Type 2 Diabetes Mellitus (DM) is on the verge of becoming a pandemic in India. Type 2 DM patient have two to four times increased risk of carotid artery disease. Adipokines have been regarded recently as direct link between diabetes and atherosclerosis. Visceral Adipose Tissue Derived Serine Protease Inhibitor (VASPIN); one of the most recently discovered adipokine, inhibits the proteases responsible for insulin resistance, carotid plaque development and rupture. In literature, few studies have addressed the role of VASPIN in pathogenesis of Acute Coronary Syndrome (ACS) in patients with type 2 DM.