Open AccessSerum Iron and Haemoglobin Estimation in Oral Submucous Fibrosis and Iron Deficiency Anaemia: A Diagnostic Approach
Author(s) -
Divya Bhardwaj,
Ajit D Dinkar,
Sujata Satoskar,
Sapna Raut Desai
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/21481.9077
Subject(s) - oral submucous fibrosis , iron deficiency , iron deficiency anemia , serum iron , medicine , gastroenterology , anemia of chronic disease , anemia , pathology
Oral Submucous Fibrosis (OSMF) is a premalignant condition with potential malignant behaviour characterized by juxta-epithelial fibrosis of the oral cavity. In the process of collagen synthesis, iron gets utilized, by the hydroxylation of proline and lysine, leading to decreased serum iron levels. The trace element like iron is receiving much attention in the detection of oral cancer and precancerous condition like OSMF as it was found to be significantly altered in these conditions.