Open AccessA Randomized Prospective Study of Concurrent Chemo-Radiotherapy vs Accelerated Hyperfractionation in Advanced Cancer of Head and Neck
Author(s) -
Himanshu Mishra,
Ritusha Mishra,
Uday Prataap Shahi,
Abhijit Mandal
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/21187.8753
Subject(s) - medicine , hyperfractionation , radiation therapy , head and neck cancer , head and neck squamous cell carcinoma , randomized controlled trial , prospective cohort study , basal cell , dose fractionation , surgery , oncology
Locally advanced unresectable squamous cell carcinoma of head and neck has poor locoregional control when treated with conventionally fractionated Radiation Therapy (RT) alone. However, Concurrent Chemo-Radiotherapy (CRT) and altered fractionated RT schedules like Accelerated Hyperfractionation (AHF) are two different treatment strategies that have shown to be associated with better efficacy as compared to conventional RT alone in such cases.