Open AccessComparison of the Effect of Clomiphene- Estradiol Valerate vs Letrozole on Endometrial Thickness, Abortion and Pregnancy Rate in Infertile Women with Polycystic Ovarian Syndrome
Author(s) -
Fariba Seyedoshohadaei,
Laleh Tangestani,
Farnaz Zandvakili,
Naser Rashadmanesh
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/20954.8324
Subject(s) - estradiol valerate , medicine , letrozole , ovulation , gynecology , menstruation , polycystic ovary , pregnancy rate , anovulation , endometrium , infertility , pregnancy , obstetrics , estrogen , hormone , tamoxifen , biology , insulin resistance , cancer , breast cancer , insulin , genetics
Clomiphene citrate is the first-line therapy for ovulation induction in Polycystic Ovarian Syndrome (PCOS). This drug binds and blocks estrogen receptors and thought to have an anti estrogenic effect on endometrium volume, thus may have adverse effect on fertility.