
Plasma Myeloperoxidase and Total Sialic Acid as Prognostic Indicators in Acute Coronary Syndrome
Author(s) -
Sumitra Govindarajan,
Vm Mithun Raghavan,
Anand C Vasudeva Rao
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/20715.8347
Subject(s) - myeloperoxidase , medicine , ejection fraction , acute coronary syndrome , unstable angina , sialic acid , myocardial infarction , heart failure , chest pain , gastroenterology , inflammation , cardiology , biochemistry , biology
Acute Coronary Syndrome (ACS) is the leading cause of death worldwide. Oxidative stress and inflammation play important role in the destabilization of plaques leading to ACS. Markers which reflect this pathophysiologic mechanism may have prognostic value. Myeloperoxidase (MPO) and Sialic acid are markers of inflammation and oxidative stress. Both these markers are increased in patients with ACS. Their prognostic value in ACS is not well established.