Open AccessHigh dose Intravenous Anti-D Immune Globulin is More Effective and Safe in Indian Paediatric Patients of Immune Thrombocytopenic Purpura
Author(s) -
Trupti Rekha Swain,
Rabindra Kumar Jena,
Kali Prasanna Swain
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/20347.8976
Subject(s) - medicine , haemolysis , thrombocytopenic purpura , platelet , immune system , adverse effect , immune thrombocytopenia , gastroenterology , gamma globulin , globulin , antibody , cumulative dose , immunology
Immune Thrombocytopenia (ITP) is characterised by an autoimmune antibody-mediated destruction of platelets and impaired platelet production. Few controlled trials exist to guide management of patients with ITP in Indian scenario for which patients require an individualized approach. Anti-D (Rho (D) immune globulin) at a higher dose can prove to be a cost effective and safe alternative for Indian patients with ITP.