High dose Intravenous Anti-D Immune Globulin is More Effective and Safe in Indian Paediatric Patients of Immune Thrombocytopenic Purpura | Zendy

Trupti Rekha Swain | Zendy; Rabindra Kumar Jena | Zendy; Kali Prasanna Swain | Zendy

Open Access

High dose Intravenous Anti-D Immune Globulin is More Effective and Safe in Indian Paediatric Patients of Immune Thrombocytopenic Purpura

Author(s) -

Trupti Rekha Swain,

Rabindra Kumar Jena,

Kali Prasanna Swain

Publication year - 2016

Publication title -

journal of clinical and diagnostic research

Language(s) - English

Resource type - Journals

eISSN - 2249-782X

pISSN - 0973-709X

DOI - 10.7860/jcdr/2016/20347.8976

Subject(s) - medicine , haemolysis , thrombocytopenic purpura , platelet , immune system , adverse effect , immune thrombocytopenia , gastroenterology , gamma globulin , globulin , antibody , cumulative dose , immunology

Immune Thrombocytopenia (ITP) is characterised by an autoimmune antibody-mediated destruction of platelets and impaired platelet production. Few controlled trials exist to guide management of patients with ITP in Indian scenario for which patients require an individualized approach. Anti-D (Rho (D) immune globulin) at a higher dose can prove to be a cost effective and safe alternative for Indian patients with ITP.

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