Open AccessChondroblastic Variant of Osteosarcoma of Mandible: Report of a Rare Case
Author(s) -
Kusuma Venkatesh,
Tushar Priyanka,
Niveditha Shankaran Rukmini,
Jagannath Bisanna
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/20150.8341
Subject(s) - craniofacial , medicine , mandible (arthropod mouthpart) , osteosarcoma , etiology , fibrous dysplasia , retinoblastoma , radiation therapy , rare disease , disease , surgery , pathology , biology , biochemistry , botany , psychiatry , gene , genus
Osteosarcoma (OS), a common malignant tumour of the long bones, is rarely seen in the craniofacial region (5-8%). Though it's aetiology is unknown, previous radiotherapy, Pagets disease, Retinoblastoma and benign bone lesions such as fibrous dysplasia are considered as predisposing factors. It is seen commonly in adults between the third and fourth decades of life, in the Gnathic location mandible. We report a rare case of chondroblastic variant of OS of the right mandible, in a 35-year-old male, who underwent right segmental mandibulectomy with fibular graft reconstruction and is having disease free survival one and half years post surgery. Craniofacial OSs, are considered a separate category in view of their low histologic grade, less frequent metastases and better prognosis. Hence the diagnosis of this variant is important. This case is reported because of its rarity and typical histopathological features.