Open AccessUnusual Case of Cerebral Venous Sinus Thrombosis in Patient with Ulcerative Colitis in Remission
Author(s) -
Lalit Kumar Meher,
Siba Prasad Dalai,
Sibasish Panda,
Pankaj Kumar Hui,
Sachidananda Nayak
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/20105.7883
Subject(s) - medicine , cerebral venous sinus thrombosis , venous thrombosis , thrombosis , ulcerative colitis , inflammatory bowel disease , pulmonary embolism , complication , gastroenterology , surgery , disease
Ulcerative colitis (UC) is an idiopathic autoimmune inflammatory disease of the gastrointestinal tract. Cerebral venous sinus thrombosis along with deep vein thrombosis, pulmonary embolism and arterial thrombosis have occasionally been reported as a complication in the active phase of UC being attributed to its pro-thrombotic state. This paper depicts a 38-year-old female with a history of UC in remission who developed sudden onset headache, blurring of vision and seizures. Subsequent diagnosis of cerebral venous sinus thrombosis was made with MRI venography and treated with low molecular weight heparin with complete resolution of symptoms. The highlights of this case underscore the importance of evaluating cerebral venous sinus thrombosis as a cause of acute onset neurological deterioration in a setting of inflammatory bowel disease. It also emphasizes on the hypothesis that the risk of venous thrombosis or other hypercoagulable states have no direct relationship with the disease activity or flare-up.