Open AccessAbnormal Nuclear Variations in Response to Radiotherapy- As a Tool in Treatment Planning and Assessment of Prognosis
Author(s) -
Kumar Satish Ravi,
Manisha Naithani,
Sukhjeet Kaur,
K. S. Reddy,
Rachna Pasi
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/19907.8338
Subject(s) - radiation therapy , medicine , oral mucosa , micronucleus test , radiosensitivity , buccal administration , nuclear medicine , micronucleus , chemotherapy , pathology , oncology , toxicity , dentistry
The treatment approaches for oral squamous cell carcinoma (OSCC) include single management with surgery, radiotherapy, along with chemotherapy or various combinations of these modalities. The estimation of radio sensitivity of individual tumours is essential for planning the optimum radiation schedule for each patient. Assessment of radiation induced histo morphological changes in the nucleus is a known marker of radiosensitivity.