Open AccessEffect of Dipyridamole Injected for Myocardial Perfusion Imaging on Blood Glucose Concentration; A Preliminary Study
Author(s) -
Amirreza Khorasanchi,
Mohsen Arabi,
A. Akhavein,
Mohammad Seyedabadi,
Mansooreh Eftekhari,
Hamid Javadi,
Iraj Nabipour,
Majid Assadi
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/19726.8373
Subject(s) - dipyridamole , medicine , perfusion , quartile , adenosine , vasodilation , microcirculation , cardiology , perfusion scanning , nuclear medicine , endocrinology , anesthesia , confidence interval
Dipyridamole inhibits adenosine reuptake and increases cyclic Adenosine Monophosphate (cAMP) levels in platelets, erythrocytes and endothelial cells, all of which influence blood glucose. Acute hyperglycaemia reduces endothelium-dependent vasodilation and suppresses coronary microcirculation; which, in theory, can alter the outcome of a radionuclide scan.