Open AccessExpression of Alpha Methylacyl CoA Racemase (AMACR) in Gastric Adenocarcinoma and Its Correlation with Helicobacter pylori Infection
Author(s) -
Yamini Jindal,
Anshul Singh,
Ravikant Kumar,
Kachnar Varma,
Vatsala Misra,
Sri Prakash Misra,
Manisha Dwivedi
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/19539.8721
Subject(s) - helicobacter pylori , adenocarcinoma , cancer , medicine , immunohistochemistry , pathology , biopsy , gastric mucosa , gastroenterology , stomach
Gastric cancer develops in a multistep progression and is determined by genetic and environmental factors. Over-expression of Alpha Methylacyl CoA Racemase (AMACR) is useful in diagnosis of prostate cancer. There is plenty of genetic alteration that occurs in gastric adenocarcinoma. The present study was planned to determine if AMACR can be used as a diagnostic marker in gastric adenocarcinoma similar to prostate cancer.