Open AccessEvaluation of IL-6, CRP and hs-CRP as Early Markers of Neonatal Sepsis
Author(s) -
P. Ganesan,
Priyadarshini Shanmugam,
Shameem Banu Abdul Sattar,
Shenbaga Lalitha Shankar
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/19214.7764
Subject(s) - sepsis , medicine , neonatal sepsis , blood culture , gastroenterology , c reactive protein , immunology , inflammation , biology , microbiology and biotechnology , antibiotics
Bacterial sepsis is a life threatening crisis with high mortality and morbidity in neonates. Due to non-specific clinical presentation, diagnosis of sepsis is still a challenge. It can be diagnosed by blood culture but it is time consuming. So, a reliable marker is needed for the diagnosis of neonatal sepsis so that early treatment can be initiated. Various cytokines, chemokines, acute phase reactants, cell surface markers and interferons have been evaluated to find out the effective marker for early diagnosis of neonatal sepsis. In this study, levels of IL-6, CRP and hs-CRP have been analysed which would favour the diagnosis of neonatal sepsis.