Open AccessComparative Study of GeneXpert with ZN Stain and Culture in Samples of Suspected Pulmonary Tuberculosis
Author(s) -
Manindra Agrawal,
Ashish Bajaj,
Vinay Bhatia,
Sarjana Dutt
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/18837.7755
Subject(s) - genexpert mtb/rif , medicine , tuberculosis , gold standard (test) , sputum , mycobacterium tuberculosis , ziehl–neelsen stain , stain , acid fast , nucleic acid amplification tests , pathology , gastroenterology , staining , immunology , chlamydia trachomatis
Tuberculosis remains one of the deadliest communicable diseases. There are number of tests available for the diagnosis of tuberculosis but conventional microscopy has low sensitivity and culture although gold standard, but takes longer time for positivity. On the other side, Nucleic acid amplification techniques due to its rapidity and sensitivity not only help in early diagnosis and management of tuberculosis especially in patients with high clinical suspicion like immunocompromised patients, history of contact with active tuberculosis patient etc., but also curtail the transmission of the disease.