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A Comparative Study of Dexmedetomidine and Midazolam in Reducing Delirium Caused by Ketamine
Author(s) -
Swati Trivedi,
Rajeev Kumar,
Aditya Kumar Tripathi,
Ranbeer Kumar Mehta
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/18397.8225
Subject(s) - premedication , dexmedetomidine , ketamine , midazolam , anesthesia , medicine , sedation , emergence delirium , glycopyrrolate , delirium , surgery , sevoflurane , atropine , intensive care medicine
Ketamine is a well known agent for sedation for short surgical procedures due to its very good analgesic action. But it has cardio stimulatory response and recovery from anaesthesia after Ketamine use is complicated by delirium and hallucination. In studies it is proved that these side effects can be reduced by premedication with benzodiazepines. The α2 adrenoceptor agonists are becoming popular for their properties like haemodynamic stability and reducing anaesthetic requirement.

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