Open AccessEvaluation of TlR2 and 4 in Chronic Periodontitis
Author(s) -
Paavai Ilango
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/18353.8027
Subject(s) - chronic periodontitis , periodontitis , tlr2 , biomarker , immune system , medicine , toll like receptor , inflammation , periodontal disease , immunology , receptor , disease , porphyromonas gingivalis , pathogenesis , tlr4 , biology , dentistry , innate immune system , genetics
Periodontal disease is the major cause of adult tooth loss and is commonly characterized by a chronic inflammation caused by infection due to oral bacteria. Members of Toll-Like Receptor (TLR) family recognize conserved microbial structures, such as bacterial lipopolysaccharides and activate signalling pathways that result in immune responses against microbial infections.