Evaluation of Protein Kinase C β and P PAR γ Activity in Diabetic Rats Supplemented with Momordica charantia | Zendy

Swetha Chandru | Zendy; Akila Prashant | Zendy; Devananda Devegowda | Zendy; Suresha Nagaraja Ramasamudra | Zendy; Basavanagowdappa Hathur | Zendy

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Evaluation of Protein Kinase C β and P PAR γ Activity in Diabetic Rats Supplemented with Momordica charantia

Author(s) -

Swetha Chandru,

Akila Prashant,

Devananda Devegowda,

Suresha Nagaraja Ramasamudra,

Basavanagowdappa Hathur

Publication year - 2016

Publication title -

journal of clinical and diagnostic research

Language(s) - English

Resource type - Journals

eISSN - 2249-782X

pISSN - 0973-709X

DOI - 10.7860/jcdr/2016/18161.7653

Subject(s) - pioglitazone , medicine , momordica , endocrinology , thiazolidinedione , streptozotocin , lipid profile , diabetes mellitus , intraperitoneal injection , alloxan , insulin , potency , type 2 diabetes , chemistry , biochemistry , traditional medicine , in vitro

The present study was taken up to compare and evaluate the effect of Momordica charantia supplementation with pioglitazone on PKC-β and PPAR-γ activity in kidneys of diabetic rats. The hypoglycaemic and lipid lowering effect of Momordica charantia were screened in laboratory animal model and its potency was compared with a Thiazolidinedione (TZD) group antidiabetic drug like pioglitazone.

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