Open AccessRequirements for Minimum Sample Size for Sensitivity and Specificity Analysis
Author(s) -
Mohamad Adam Bujang,
Tassha Hilda Adnan
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/18129.8744
Subject(s) - sample size determination , sensitivity (control systems) , type i and type ii errors , statistics , sample (material) , statistical power , computer science , power analysis , mathematics , data mining , algorithm , engineering , chromatography , chemistry , electronic engineering , cryptography
Sensitivity and specificity analysis is commonly used for screening and diagnostic tests. The main issue researchers face is to determine the sufficient sample sizes that are related with screening and diagnostic studies. Although the formula for sample size calculation is available but concerning majority of the researchers are not mathematicians or statisticians, hence, sample size calculation might not be easy for them. This review paper provides sample size tables with regards to sensitivity and specificity analysis. These tables were derived from formulation of sensitivity and specificity test using Power Analysis and Sample Size (PASS) software based on desired type I error, power and effect size. The approaches on how to use the tables were also discussed.