
Correlation of α -Lipoic Acid and S. Glutathione Level with Free Radical Excess in Tobacco Consumers
Author(s) -
Satyawati Sharma
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/18039.7577
Subject(s) - malondialdehyde , glutathione , lipid peroxidation , oxidative stress , lipoic acid , antioxidant , cigarette smoking , medicine , hazard ratio , chewing tobacco , physiology , chemistry , biochemistry , enzyme , confidence interval , cancer
Tobacco consumption is a serious health hazard and most important avoidable cause of death worldwide. Tobacco is recognized as lethal toxin, ripping off 7-11 minutes of human life with each cigarette through harmful compounds and inducing free radical synthesis and a high rate of lipid peroxidation. These free radicals are scavenged by the endogenous antioxidants viz. S. Glutathione (S.GSH) and S. α-Lipoic acid (S. α-LA), thus preventing the endothelial damage.