Open AccessCombined Arterial and Venous Thrombosis in Ulcerative Colitis- A Rare Vascular Manifestation
Author(s) -
Harpreet Singh,
Pranav Ish,
Richa Dewan,
S Anuradha,
Sumeet Singla
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/17906.7608
Subject(s) - medicine , ulcerative colitis , venous thrombosis , gangrene , thrombosis , sepsis , surgery , shock (circulatory) , colitis , septic shock , disease
Combined arterial and venous thrombosis in patients with ulcerative colitis is a rare extra vascular manifestation, which motivated the current report. Increased coagulability is a recognised feature of ulcerative colitis with frequency increasing during flares. We report the case of a 42-year-old lady who was a diagnosed case of ulcerative colitis, currently in remission. She presented with swelling followed by discolouration of left lower limb which later was diagnosed as deep venous thrombosis combined with femoral and popliteal artery thrombosis. This led to wet gangrene of the limb, sepsis, septic shock and death despite aggressive management with heparin infusion, ionotropes, and parenteral antibiotics therapy.