Impact of Seasonal Variant Temperatures and Laboratory Room Ambient Temperature on Mortality of Rats with Ischemic Brain Injury | Zendy

Sivakumar Gopalakrishanan | Zendy; M. G. Ramesh Babu | Zendy; Rajesh Thangarajan | Zendy; Dhiren Punja | Zendy; Vidyadhara Devarunda Jaganath | Zendy; Akriti Baby Kanth | Zendy; Mohandas Kg Rao | Zendy; S. Kiranmai | Zendy

Open Access

Impact of Seasonal Variant Temperatures and Laboratory Room Ambient Temperature on Mortality of Rats with Ischemic Brain Injury

Author(s) -

Sivakumar Gopalakrishanan,

M. G. Ramesh Babu,

Rajesh Thangarajan,

Dhiren Punja,

Vidyadhara Devarunda Jaganath,

Akriti Baby Kanth,

Mohandas Kg Rao,

S. Kiranmai

Publication year - 2016

Publication title -

journal of clinical and diagnostic research

Language(s) - English

Resource type - Journals

eISSN - 2249-782X

pISSN - 0973-709X

DOI - 10.7860/jcdr/2016/17372.7597

Subject(s) - medicine , anesthesia , ketamine , zoology , biology

A popular rat model for hypoperfusion ischemic brain injury is bilateral common carotid artery occlusion (BCCAO). BCCAO surgery when performed in varying geographical locations and during different seasons of the year is reported to have variable mortality rates. Studies have also documented the diminishing influence of Ketamine-Xylazine (KT-XY) on thermoregulatory functions in rodents.

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