Open AccessImpact of Seasonal Variant Temperatures and Laboratory Room Ambient Temperature on Mortality of Rats with Ischemic Brain Injury
Author(s) -
Sivakumar Gopalakrishanan,
M. G. Ramesh Babu,
Rajesh Thachathodiyl,
Dhiren Punja,
Vidyadhara Devarunda Jaganath,
Akriti Baby Kanth,
Muddanna S. Rao,
S. Kiranmai
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/17372.7597
Subject(s) - medicine , anesthesia , ketamine , zoology , biology
A popular rat model for hypoperfusion ischemic brain injury is bilateral common carotid artery occlusion (BCCAO). BCCAO surgery when performed in varying geographical locations and during different seasons of the year is reported to have variable mortality rates. Studies have also documented the diminishing influence of Ketamine-Xylazine (KT-XY) on thermoregulatory functions in rodents.