Open AccessSelective Serotonin Re-uptake Inhibitors (SSRIs) Induced Weight Changes: A Dose and Duration Dependent Study on Albino Rats
Author(s) -
Alka Aggarwal,
S L Jethani,
R K Rohatgi,
Juhi Kalra
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/16482.7376
Subject(s) - fluoxetine , saline , serotonin , body weight , medicine , intraperitoneal injection , weight loss , endocrinology , pharmacology , anesthesia , obesity , receptor
Selective Serotonin Re-uptake Inhibitors (SSRIs) are the most significant and safe drugs among the antidepressants. Fluoxetine is the prototype drug of SSRIs. Various clinical studies showed that SSRI causes change in body weight in patients. This study was conducted to know the extent of weight change with different doses for different durations.