Open AccessFallacious Carcinoma- Spindle Cell Variant of Squamous Cell Carcinoma
Author(s) -
Radhika M Bavle,
Girish Govinda,
Padmalatha Gundappanayakanahalli Venkataramanaiah,
M Sudhakara,
R. Venugopal
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - Uncategorized
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/16400.8099
Subject(s) - immunohistochemistry , pathology , basal cell , spindle cell carcinoma , carcinoma , medicine , metastasis , head and neck , head and neck squamous cell carcinoma , cell , sarcoma , biology , cancer , head and neck cancer , surgery , genetics
Spindle cell carcinoma is a unique, rare and peculiar biphasic tumour of head and neck which is not frequently observed in the oral cavity. This variant of squamous cell carcinoma although of monophasic epithelial origin, simulates a sarcoma and is an aggressive carcinoma with high frequency of recurrence and metastasis. A correct and timely diagnosis is of paramount importance. Most of the tumours require an Immunohistochemistry (IHC) panel for confirmation or diagnosis. We report a case of spindle cell carcinoma with varied histopathological morphology and clinical presentation in a middle aged female with a brief review of literature.