Open AccessExchange Transfusion in Severe Falciparum Malaria
Author(s) -
Harshad C Dongare,
Khalid Khatib
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - Uncategorized
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/16341.7190
Subject(s) - malaria , artesunate , medicine , severe malaria , exchange transfusion , plasmodium falciparum , ards , incidence (geometry) , blood transfusion , intensive care medicine , immunology , lung , physics , optics
Malaria is endemic in India with the incidence of P. falciparum Malaria increasing gradually over the last decade. Severe malaria is an acute disease, caused by P. falciparum, but increasingly also by P. vivax with major signs of organ dysfunction and/or high levels of parasitaemia (>10%) in blood smear. Use of exchange transfusion with antimalarial drug therapy as an additional modality of treatment in severe Falciparum malaria is controversial and is unclear. We report a case of severe malaria complicated by multiorgan failure and ARDS. Patient responded well to manual exchange transfusion with standard artesunate-based chemotherapy.