Open AccessEvaluation of Renal Allograft Biopsies for Graft Dysfunction and Relevance of C4d Staining in Antibody Mediated Rejection
Author(s) -
Clement Wilfred Devadass,
A V Vanikar,
Lovelesh K. Nigam,
Kamal V Kanodia,
Rashmi D Patel,
Kyasakkala Sannaboraiah Vinay,
Himanshu V. Patel
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/16339.7433
Subject(s) - medicine , biopsy , pathology , peritubular capillaries , calcineurin , transplantation , immunohistochemistry , gold standard (test) , gastroenterology
Biopsy remains gold standard for diagnosis of Graft Dysfunction (GD). It guides clinical management, provides valuable insights into pathogenesis of early and late allograft injury and is indispensable for distinguishing rejection from non- rejection causes of GD.