Open AccessStudy of Aplastic Anaemia with Cyclosporine in Resource Poor Setting
Author(s) -
Meenakshi Shetty,
A Narendra,
Krishna Prasad Adiraju,
N.R. Modugu
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/16144.7952
Subject(s) - medicine , pancytopenia , aplastic anemia , cyclophosphamide , pallor , immunosuppression , surgery , gastroenterology , bone marrow , chemotherapy , pediatrics
Aplastic Anaemia (AA) is a syndrome characterized by peripheral pancytopenia with hypo-cellular marrow. Acquired idiopathic AA is the most common variety, probably of an autoimmune aetiology. Bone Marrow Transplantation (BMT) is the treatment of choice but cost is the limiting factor. Antithymocyte Globulin and Cyclosporine-A is an alternative to BMT. Cyclosporine alone has been tried as a single agent in resource poor setting.