Correlation of Oxidative Damage with Pro-Inflammatory Markers (IL-6, TNF- α ) in Meningocele | Zendy

Bedabrata Mukhopadhyay | Zendy; Roshni Gavel | Zendy; Ajay N Gongopadhyay | Zendy; Pooja Vashistha | Zendy; Anjali Rani | Zendy; Surendra Pratap Mishra | Zendy

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Correlation of Oxidative Damage with Pro-Inflammatory Markers (IL-6, TNF- α ) in Meningocele

Author(s) -

Bedabrata Mukhopadhyay,

Roshni Gavel,

Ajay N Gongopadhyay,

Pooja Vashistha,

Anjali Rani,

Surendra Pratap Mishra

Publication year - 2016

Publication title -

journal of clinical and diagnostic research

Language(s) - English

Resource type - Journals

eISSN - 2249-782X

pISSN - 0973-709X

DOI - 10.7860/jcdr/2016/15872.7229

Subject(s) - medicine , superoxide dismutase , oxidative stress , oxidative damage , tumor necrosis factor alpha , gastroenterology

Oxidative damage induces alteration in the status of pro-inflammatory markers like IL-6 and TNF-α in meningocele. The study was performed with estimation of the levels of MDA (Malonyldialdehyde), SOD (Superoxide dismutase) taken as oxidative damage markers and IL-6 (interleukin 6) and TNF-α (Tumour necrosis factor alpha) taken as inflammatory markers, in the serum of meningocele patients and age, sex matched normal neonates. Correlation among the different serum levels of MDA, SOD, IL-6 and TNF-α was determined.

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