Open AccessCorrelation of Oxidative Damage with Pro-Inflammatory Markers (IL-6, TNF- α ) in Meningocele
Author(s) -
Bedabrata Mukhopadhyay,
Roshni Gavel,
Ajay Narayan Gongopadhyay,
Pooja Vashistha,
Anjali Rani,
Sarita Mishra
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/15872.7229
Subject(s) - medicine , superoxide dismutase , oxidative stress , oxidative damage , tumor necrosis factor alpha , gastroenterology
Oxidative damage induces alteration in the status of pro-inflammatory markers like IL-6 and TNF-α in meningocele. The study was performed with estimation of the levels of MDA (Malonyldialdehyde), SOD (Superoxide dismutase) taken as oxidative damage markers and IL-6 (interleukin 6) and TNF-α (Tumour necrosis factor alpha) taken as inflammatory markers, in the serum of meningocele patients and age, sex matched normal neonates. Correlation among the different serum levels of MDA, SOD, IL-6 and TNF-α was determined.