Open AccessDisseminated Histoplasmosis with Haemophagocytic Lymphohistiocytosis in an Immunocompetent Host
Author(s) -
Amey Sonavane,
Pratibha Sonawane,
Sachet V. Chandak,
Pravin Rathi
Publication year - 2016
Publication title -
journal of clinical and diagnostic research
Language(s) - English
Resource type - Journals
eISSN - 2249-782X
pISSN - 0973-709X
DOI - 10.7860/jcdr/2016/15839.7337
Subject(s) - histoplasmosis , hemophagocytic lymphohistiocytosis , medicine , immunology , immune system , disease , pathology
Haemophagocytic lymphohistiocytosis (HLH) is a devastating syndrome due to uninhibited immune activation. Disseminated histoplasmosis is a rare cause of HLH. There have been few case reports and series demonstrating a relation between the two disease entities in immunosuppressed hosts. HLH secondary to disseminated histoplasmosis is even rarer in an immunocompetant host. We report a rare case of HLH triggered by disseminated histoplasmosis in an immunocompetant patient.